Le Duc Hau

Associate Professor
Head, Bioinformatics Lab

Ph.D. (Computer Engineering, University of Ulsan, 2012)
M.S. (Information Processing and Communication, Hanoi University of Technology, 2008)
B.E. (Electronics and Telecommunications, Hanoi University of Technology, 2002)

Email: hauld@soict.hust.edu.vn
Websites:
https://scholar.google.com.vn/citations?user=ko2EXGcAAAAJ&hl=en
https://sites.google.com/view/duchaule/home 

• Bioinformatics
• Computational Biomedicine
• Artificial Intelligence

• Computational methods for the identification of novel disease-associated biomarkers.
• Computational Personalized Medicine/Pharmacogenomics
• Computational Drug Discovery
• Genome Analysis
• Complex Network Analysis

Assoc. Prof. Duc-Hau Le obtained his Ph.D. degree in Bioinformatics from the University of Ulsan, Republic of Korea, in 2012. He now leads the Bioinformatics Lab at the BK.AI Center, School of Information and Communications Technology, Hanoi University of Science and Technology, Vietnam. His research focuses on proposing computational methods for disease- and drug-related problems in personalized medicine and drug discovery, especially the identification of disease-associated biomarkers and the prediction of drug targets and drug response. In parallel, he has developed bioinformatics tools the research and biomedical application communities. So far, he has published more than sixty papers in well-recognized journals and conferences, most of which are in ISI-indexed journals. In addition, he has served as a member of program committees and a reviewer for prestigious international conferences and journals. Moreover, he is a principal investigator and a key member of several national/ministry-level projects. Notably, he is the principal investigator of the biggest genome project in Vietnam (i.e., building databases of genomic variants for the Vietnamese population, https://genome.vinbigdata.org).

• Duc-Hau Le, Trinh H-C, Quynh TD, Doan TC: The interplay of assortativity, centrality, and robustness in human signaling networks: Implications for drug discovery. Chaos, Solitons & Fractals 2025, 194:116254.
• Hoa Thi Phuong Bui,Duong Huy Do,Ha Thi Thanh Ly,Kien Trung Tran,Huong Thi Thanh Le,Kien Trung Nguyen,Linh Thi Dieu Pham, Duc-Hau Le,Vinh Sy Le,Arijit Mukhopadhyay ,Liem Thanh Nguyen (2023) De novo Copy Number variations in candidate genomic regions in patients of severe autism spectrum disorder in Vietnam, PLOS ONE, 19(3):e0290936
• Quang-Huy Nguyen, Duc-Hau Le (2022) oCEM: Automatic detection and analysis of overlapping co-expressed gene modules, BMC Genomics, 2022. 23(1):39
• Quang-Huy Nguyen, Tin Nguyen, Duc-Hau Le (2022) DrGA: cancer driver gene analysis in an automatic manner, BMC Bioinformatics, 2022;23(1):86.
• Quang-Huy Nguyen, Tin Nguyen, Duc-Hau Le (2022) Identification and validation of a novel three hub long noncoding RNAs with m6A modification signature in low-grade gliomas, Frontiers in Molecular Biosciences, 2022 Vol. 9 
• Duc-Hau Le, Quang-Huy Nguyen, Lan T.M. Dao (2022) Computational and Experimental Approaches in Exploring the Role of Genetics and Genomics in Multifactorial Diseases, Frontiers in Genetics, 2022 Vol. 13 .
• Giang T.T. Nguyen, Hoa D. Vu and Duc-Hau Le (2021) Integrating molecular graph data of drugs and multiple -omics data of cell lines for drug response prediction, IEEE/ACM Transactions on Computational Biology and Bioinformatics doi: 10.1109/TCBB.2021.3096960
• Tuan Nguyen, Giang T.T. Nguyen, Thin Nguyen and Duc-Hau Le (2021) Graph convolutional networks for drug response prediction, IEEE/ACM Transactions on Computational Biology and Bioinformatics, Vol. 19 Issue 1 Pages 146-154, DOI: 10.1109/TCBB.2021.3060430
• Duc-Hau Le (2021) A network-based method for predicting disease-associated enhancers, PLOS ONE, 16(12): e0260432. https://doi.org/10.1371/journal.pone.0260432
• Yen T.H. Nguyen, Quang-Huy Nguyen, Tin Nguyen, Duc-Hau Le (2021) Re-identification of patient subgroups in Uveal Melanoma, Frontiers in Oncology, 11:731548 

• ET4596E: Bioinformatics
• IT5428: Generative AI in BioInformatics, Medicine and Healthcare
• IT5427E: Big Data Integration and Processing
• IT5421E: Seminar 01
• IT3040: Programming Techniques
• IT3290E: Database Lab
• IT3034: Computer Architectures
• IT3103: Object-oriented Programming
• IT1110E: Introduction to Programming